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Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients. There are three general classes of drugs commonly used in the treatment of rheumatoid arthritis: non-steroidal anti-inflammatory agents NSAIDs, corticosteroids, and disease modifying anti-rheumatic drugs DMARDs. Other immunomodulators are occasionally used including azathioprine Imuran and cyclosporine. A summary table of how to monitor drug treatment in rheumatoid arthritis is included. The major effect of these agents is to reduce acute inflammation thereby decreasing pain and improving function. All of these drugs also have mild to moderate analgesic properties independent of their anti-inflammatory effect.

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