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Therapeutic, effective treatment of obesity requires a substantial and long-term at least one year reduction in body weight. In a number of short-term studies with relatively few patients, weight loss has been has been noted. It has been suggested by some marketing authorization holders that a short-term reduction in body weight as part of a program to treat obesity may be useful. After treatment is discontinued, there is Buy adipex The main safety concerns discussed relate to serious side effects on the central nervous system, primary pulmonary hypertension, and valvular Cardiac valve changes when used as directed.

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