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These medications are designed to be used by individuals suffering from obesity. Alternately, they may also be prescribed to people who are overweight and whose excess body fat is increasing their risk of serious health conditions. Those conditions may include heart disease, some cancers or diabetes. This drug is not prescribed to people who are merely seeking cosmetic weight loss. It is a serious medication that comes with considerable potential benefits, as well as some significant possible risks.
An inexpensive weight-loss drug approved 60 years ago for only short-term use also may be safe and effective for longer-term treatment, according to a study conducted by researchers at Wake Forest Baptist Health and the Patient Outcomes Research to Advance Learning PORTAL network. Most new weight-loss drugs are approved for long-term use, but unfortunately the newer drugs can be expensive if they are not covered by insurance. The researchers compared weight loss and changes in blood pressure for up to two years, and the risk of heart attack, stroke or death for up to three years, according to a patient's duration of medication use.
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Common side effects include a fast heart beat, high blood pressure, trouble sleeping, dizziness, and restlessness. Tolerance usually occurs; however, risks of dependence and addiction are considered negligible.
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This chapter discusses the processes of administration, absorption, distribution, metabolism and excretion of drugs together with factors affecting these processes. Collectively, these processes describe drug disposition, the way in which the body handles drugs.
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